Darm

Mucosal Flora
Functional biostructure of colonic microbiota
Diagnose and monitoring of active Crohn's disease and ulcerative colitis
Kurzfassung in Deutsch
Alexander Swidsinski Dickdarm-Mikrobiom und S. boulardii. Medical Tribune Austria 2018 Nr.51-52 (4) 19. Dezember 2018
Swidsinski A, Dörffel Y, Loening-Baucke V, Gille C, Göktas Ö, Reißhauer A, Neuhaus J, Weylandt KH, Guschin A, Bock M. Reduced Mass and Diversity of the Colonic Microbiome in Patients with Multiple Sclerosis and Their Improvement with Ketogenic Diet. Front Microbiol. 2017 Jun 28;8:1141. doi: 10.3389/fmicb.2017.01141. eCollection 2017. PMID: 28702003
Swidsinski A, Dörffel Y, Loening-Baucke V, Gille C, Reißhauer A, Göktas O, Krüger M, Neuhaus J, Schrödl W. Impact of humic acids on the colonic microbiome in healthy volunteers World J Gastroenterol. 2017 Feb 7;23(5):885-890. doi: 10.3748/wjg.v23.i5.885. PMID: 28223733
Alexander Swidsinski and Vera Loening-Baucke Evaluation of Polymicrobial Involvement Using Fluorescence In Situ Hybridization (FISH) in Clinical PracticeFluorescence In Situ Hybridization (FISH) - Application Guide. Edited by T. Liehr. 2017, pp 606, Eur 114.39, ISBN: 978-3-662-52957-7. Springer-Verlag, Berlin, Germany.
Swidsinski A, Loening-Baucke V, Schulz S, Manowsky J, Verstraelen H, Swidsinski S. Functional anatomy of the colonic bioreactor: Impact of antibiotics and Saccharomyces boulardii on bacterial composition in human fecal cylinders. Syst Appl Microbiol. 2016 Feb;39(1):67-75. doi: 10.1016/j.syapm.2015.11.002. Epub 2015 Dec 14. PMID:26723852
Margret I Moré, Alexander Swidsinski Saccharomyces boulardii CNCM I-745 supports regeneration of the intestinal microbiota after diarrheic dysbiosis – a review. Clinical and Experimental Gastroenterology 2015 Aug; 8:237-255.
Swidsinski A, Loening-Baucke V, Krüger M, Kirsch S. SCentral Nervous System and the Colonic Bioreactor: Analysis of Colonic Microbiota in Patients with Stroke Unravels Unknown Mechanisms of the Host Defense after Brain Injury. Intest Res 2012;10(4):332-342
Swidsinski A, Dörffel Y, Loening-Baucke V, Tertychnyy A, Biche-Ool S, Stonogin S, Guo Y, Sun ND. Mucosal Invasion by Fusobacteria is a Common Feature of Acute Appendicitis in Germany, Russia, and China. Saudi J Gastroenterol 2012 Jan;18(1):55-8. PubMed PMID: 22249094
Femia AP, Swidsinski A, Dolora P, Salvatori M, Amedei A, Caderni G. Mucin Depleted Foci, Colonic Preneoplastic Lesions Lacking Muc2, Show Up-Regulation of Tlr2 but Not Bacterial Infiltration. PLoS One. 2012;7(1):e29918. Epub 2012 Jan 5 PubMed PMID: 22242189
Dörffel Y, Swidsinski A, Loening-Baucke V, Wiedenmann B, Marianne Pavel M. Common Biostructure of the Colonic Microbiota in Neuroendocrine Tumors and Crohn’s Disease and the Effect of Therapy. Inflamm Bowel Dis. 2011 Nov 23. doi: 10.1002/ibd.21923. [Epub ahead of print] PubMed PMID: 22113988
Mengel H, Kruger M, Kruger M U,Westphal B, Swidsinski A, Schwarz S, Mundt HC, Dittmar K, Daugschies A. Necrotic enteritis due to simultaneous infection with Isospora suis and clostridia in newborn piglets and its prevention by early treatment with toltrazuril. Parasitol Res 2011 Oct 4. [Epub ahead of print] PubMed PMID: 21968954
Swidsinski A, Loening-Baucke V, Kirsch S, Doerffel Y. MFunctional biostructure of colonic microbiota (central fermenting area, germinal stock area and separating mucus layer) in healthy subjects and patients with diarrhea treated with Saccharomyces boulardii. Gastroenterol Clin Biol. 2010 Sep;34 Suppl 1:S79-92. French. PubMed PMID: 20889010.
Swidsinski A, Loening-Baucke V, Herber A Mucosal flora in Crohn's disease and ulcerative colitis - an overview. J Physiol Pharmacol. 2009 Dec;60 Suppl 6:61-71.PubMed PMID: 20224153.
Swidsinski A, Dörffel Y, Loening-Baucke V, Theissig F, Rückert JC, Ismail M, Rau WA, Gaschler D, Weizenegger M, Kühn S, Schilling J, Dörffel WV. Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum. Gut. 2010 May 4. [Epub ahead of print] PubMed PMID: 19926616.
SKrüger M, Schroedl W, Krüger M, Schwarz S, Mengel H, Daugschies A, Swidsisnki A, Mundt HC, Westphahl B. Nekrotische Enteritis bei Saugferkeln durch Interaktion von Isospora suis und Clostridium perfringens Der Praktische Tierarzt 91, Heft 9, 774-84 (2010)
Swidsinski A, Ung V, Sydora BC, Loening-Baucke V, Doerffel Y, Verstraelen H, Fedorak RN. Bacterial overgrowth and inflammation of small intestine after carboxymethylcellulose ingestion in genetically susceptible mice. Inflamm Bowel Dis. 2009 Mar;15(3):359-64. PubMed PMID: 18844217.
Swidsinski A, Loening-Baucke V, Verstraelen H, Osowska S, Doerffel Y. Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea. Gastroenterology. 2008 Aug;135(2):568-79. Epub 2008 Apr 18. PubMed PMID: 18570896.
SDöerffel Y, Pavel M, Loening-Baucke V, Swidsinski A. Common biostructure of the fecal flora in celiac disease, Crohn's disease, and carcinoid tumors. Inflamm Bowel Dis. 2008 Nov;14(11):1613-4. PubMed PMID: 18521905.
Loening-Baucke V, Swidsinski A. Observational study of children with aerophagia. Clin Pediatr (Phila). 2008 Sep;47(7):664-9. Epub 2008 Apr 29. PubMed PMID: 18445758.
Swidsinski A, Loening-Baucke V, Bengmark S, Scholze J, Doerffel Y. Bacterial biofilm suppression with antibiotics for ulcerative and indeterminate colitis: consequences of aggressive treatment. Arch Med Res. 2008 Feb;39(2):198-204. Epub 2007 Oct 31. PubMed PMID: 18164963.
Swidsinski A, Loening-Baucke V, Vaneechoutte M, Doerffel Y. Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora. Inflamm Bowel Dis. 2008 Feb;14(2):147-61. PubMed PMID: 18050295.
Loening-Baucke V, Swidsinski A. Constipation as cause of acute abdominal pain in children. J Pediatr. 2007 Dec;151(6):666-9. Epub 2007 Jul 30. PubMed PMID: 18035149.
Sandek A, Bauditz J, Swidsinski A, Buhner S, Weber-Eibel J, von Haehling S, Schroedl W, Karhausen T, Doehner W, Rauchhaus M, Poole-Wilson P, Volk HD, Lochs H, Anker SD. Altered intestinal function in patients with chronic heart failure. J Am Coll Cardiol. 2007 Oct 16;50(16):1561-9. Epub 2007 Oct 1. PubMed PMID: 17936155.
Eaves-Pyles T, Allen CA, Taormina, Swidsinski A, Tutt CB, Jezek GE, Islas-Islas M, Torres AG. Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells. Int J Med Microbiol. 2008 Jul;298(5-6):397-409. Epub 2007 Sep 27. PubMed PMID: 17900983.
Swidsinski A, Sydora BC, Doerffel Y, Loening-Baucke V, Vaneechoutte M, Lupicki M, Scholze J, Lochs H, Dieleman LA. Viscosity gradient within the mucus layer determines the mucosal barrier function and the spatial organization of the intestinal microbiota. Inflamm Bowel Dis. 2007 Aug;13(8):963-70. PubMed PMID: 17455202.
Swidsinski A, Loening-Baucke V, Bengmark S, Lochs H, Dörffel Y. Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitis. Inflamm Bowel Dis. 2007 Jan;13(1):51-6. PubMed PMID: 17206639.
Swidsinski A. Standards for bacterial identification by fluorescence In situ hybridization within eukaryotic tissue using ribosomal rRNA-based probes. Inflamm Bowel Dis. 2006 Aug;12(8):824-6; author reply 826-7. PubMed PMID: 16917237.
Swidsinski A, Loening-Baucke V, Theissig F, Engelhardt H, Bengmark S, Koch S, Lochs H, Dörffel Y. Comparative study of the intestinal mucus barrier in normal and inflamed colon. Gut. 2007 Mar;56(3):343-50. Epub 2006 Aug 14. PubMed PMID: 16908512; PubMed Central PMCID: PMC1856798.
Canny G, Swidsinski A, McCormick BA. Interactions of intestinal epithelial cells with bacteria and immune cells: methods to characterize microflora and functionalconsequences. Methods Mol Biol. 2006;341:17-35. Review. PubMed PMID: 16799186.
Hale LP, Gottfried MR, Swidsinski A. Piroxicam treatment of IL-10-deficient mice enhances colonic epithelial apoptosis and mucosal exposure to intestinal bacteria. Inflamm Bowel Dis. 2005 Dec;11(12):1060-9. PubMed PMID: 16306768.
Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H. Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol. 2005 Jul;43(7):3380-9. PubMed PMID: 16000463; PubMed Central PMCID: PMC1169142.
Swidsinski A, Loening-Baucke V, Lochs H, Hale LP. Spatial organization of bacterial flora in normal and inflamed intestine: a fluorescence in situ hybridization study in mice. World J Gastroenterol. 2005 Feb 28;11(8):1131-40. PubMed PMID: 15754393.
Darfeuille-Michaud A, Boudeau J, Bulois P, Neut C, Glasser AL, Barnich N, Bringer MA, Swidsinski A, Beaugerie L, Colombel JF. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology. 2004 Aug;127(2):412-21. PubMed PMID: 15300573.
Swidsinski A, Ladhoff A, Pernthaler A, Swidsinski S, Loening-Baucke V, Ortner M, Weber J, Hoffmann U, Schreiber S, Dietel M, Lochs H. Mucosal flora in inflammatory bowel disease. Gastroenterology. 2002 Jan;122(1):44-54. PubMed PMID: 11781279.
Swidsinski A, Lee SP. The role of bacteria in gallstone pathogenesis. Front Biosci. 2001 Oct 1;6:E93-103. Review. PubMed PMID: 11578976.
Swidsinski A, Khilkin M, Kerjaschki D, Schreiber S, Ortner M, Weber J, Lochs H. Association between intraepithelial Escherichia coli and colorectal cancer. Gastroenterology. 1998 Aug;115(2):281-6. PubMed PMID: 9679033.
Swidsinski A, Dörffel Y, Loening-Baucke V, Tertychnyy A, Biche-Ool S, Stonogin S, Guo Y, Sun ND. Mucosal Invasion by Fusobacteria is a Common Feature of Acute Appendicitis in Germany, Russia, and China. Saudi J Gastroenterol 2012 Jan;18(1):55-8. PubMed PMID: 22249094
Swidsinski A, Dörffel Y, Loening-Baucke V, Theissig F, Rückert JC, Ismail M, Rau WA, Gaschler D, Weizenegger M, Kühn S, Schilling J, Dörffel WV. Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum. Gut. 2010 May 4. [Epub ahead of print] PubMed PMID: 19926616
A. Swidsinski,M. Khilkin,D. Kerjaschki,S.Schreiber,M. Ortner, Jutta Weber,H. Lochs Association Between Intraepithelial Escherichia coliand Colorectal Cancer GASTROENTEROLOGY 1998;115:281–286